Treating Tuberculosis: Time to Introduce Fixed-Dose Drug Combinations
نویسندگان
چکیده
منابع مشابه
Treating Tuberculosis: Time to Introduce Fixed-Dose Drug Combinations
Improvised formulation technology In the early 1990s, FDCs of antitubercular drugs were not advocated because of their relatively poor bioavailability and short shelf life. [3] With the present improved formulation technologies, the currently available FDCs are bioequivalent to single drug reference products. Moreover, the stability of these FDCs even after six months in tropical countries is w...
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BACKGROUND People who are newly diagnosed with pulmonary tuberculosis (TB) typically receive a standard first-line treatment regimen that consists of two months of isoniazid, rifampicin, pyrazinamide, and ethambutol followed by four months of isoniazid and rifampicin. Fixed-dose combinations (FDCs) of these drugs are widely recommended. OBJECTIVES To compare the efficacy, safety, and acceptab...
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ژورنال
عنوان ژورنال: Journal of Young Pharmacists
سال: 2012
ISSN: 0975-1483
DOI: 10.4103/0975-1483.104362